Effect of Cell Labeling on the Function of Human Pluripotent Stem Cell-Derived Cardiomyocytes
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چکیده
منابع مشابه
Maturation of Human Pluripotent Stem Cell–Derived Cardiomyocytes
In the past 6 years, multiple laboratories have reported the successful directed cardiomyocyte differentiation from human pluripotent stem cells (hPSCs; reviewed in Burridge et al). These stem cell–derived cardiomyocytes beat spontaneously, express the expected sarcomeric proteins and ion channels, and exhibit cardiac-type action potentials and calcium transients. They show similar functional p...
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Human pluripotent stem cell-derived cardiomyocytes (hPSC-CM) represent a potential unlimited cell supply for cardiac tissue engineering and possibly regenerative medicine applications. However, hPSC-CMs produced by current protocols are not representative of native adult human cardiomyocytes as they display immature gene expression profile, structure and function. In order to improve hPSC-CM ma...
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ژورنال
عنوان ژورنال: International Journal of Stem Cells
سال: 2020
ISSN: 2005-5447
DOI: 10.15283/ijsc19138